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CialisErectile dysfunction or impotence is a sexual dysfunction CIALIS is a medicine for the treatment of erectile dysfunction Interactions with other medications Cialis drug historyFDA approved Cialis in November 21, 2003. In 1993 the drug company Icos began studying IC351, which is a PDE5 enzyme inhibitor, and this is basically the process through which the erectile dysfunction drugs work. Icos received its very first patent in 1994 on IC351, and the clinical trials of phase 1 took place in 1995. In 1997, phase II clinical studies began and Icos performed its first study on patients with erectile dysfunction. Phase II lasted about two years, and after that phase III began. In 1998, ICOS Corporation, and Eli Lilly and Company, commercialized the drug for erectile dysfunction, and two years later they filed a new drug application with the U.S. Food and Drug Administration for IC351; they decided to call the drug, Cialis. In May of 2002, Icos and Eli Lilly and Company reported to the American Urological Association that the phase III tests show that Cialis works for up to 36 hours, and one year later Icos and Eli Lilly and Company received the U.S. FDA's approval for Cialis. Eli Lilly purchased ICOS corporation for $2.1 billion dollars in 2006.
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